Prepulse inhibition of the blink reflex is abnormal in functional movement disorders

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Reflex excitability regulates prepulse inhibition.

Presentation of a weak stimulus, a prepulse, before a reflex-evoking stimulus decreases the amplitude of the reflex response relative to reflex amplitude evoked without a preceding prepulse. For example, presenting a brief tone before a trigeminal blink-eliciting stimulus significantly reduces reflex blink amplitude. A common explanation of such data are that sensory processing of the prepulse ...

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Facilitation as well as inhibition of the blink reflex by a visual prepulse requires intact striate cortex.

OBJECTIVE The role of visual cortex in modulation of the human eye blink reflex was assessed. METHODS Participants were 13 patients with unilateral striate cortex damage. Nonreflexogenic gratings were presented in their intact or blind hemifield prior to white noise or air puff blink-eliciting stimuli. RESULTS Inhibition of reflex amplitude was observed at asynchronies ranging from about 12...

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The human blink reflex.

A detailed study of the human blink reflex in the different parts of the orbicularis oculi muscle has been carried out. The first component of the blink reflex has been demonstrated in patients with Friedreich's ataxia, who have selective loss of large sensory fibres resulting in loss of proprioceptive input. It has been established that both components of the blink reflex are cutaneous reflexe...

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ژورنال

عنوان ژورنال: Movement Disorders

سال: 2019

ISSN: 0885-3185,1531-8257

DOI: 10.1002/mds.27706